Publications – Selcan Aydin

Simplifying Systems Genetics with QTLretrievR: An R Package for Molecular QTL Identification

Article

Hannah B. Dewey, Selcan Aydin, Samuel J. Widmayer, Daniel A. Skelly, Daniel M. Gatti, Steven C. Munger

Cross cell-type systems genetics reveals the influence of eQTL at multiple points in the developmental trajectory of mouse neural progenitor cells

Preprint

Selcan Aydin, Daniel A. Skelly, Hannah B. Dewey, J. Matthew Mahoney, Ted Choi, Laura G. Reinholdt, Christopher L. Baker, Steven C. Munger

Systems genetics reveals the influence of expression QTLs in mouse embryonic stem cells on transcriptional variation later in differentiated neural progenitor cells

Article

G3 Genes Genomes Genetics · 2025

Selcan Aydin, Daniel A. Skelly, Hannah B. Dewey, J. Matthew Mahoney, Ted Choi, Laura G. Reinholdt, Christopher L. Baker, Steven C. Munger

G3 Genes Genomes Genetics

An in vitro neurogenetics platform for precision disease modeling in the mouse

Article

Science Advances · 2024

Daniel Cortés, Mélanie Escudero, Austin C. Korgan, Arojit Mitra, Alyssa Edwards, Selcan Aydin, Steven C. Munger, Kevin Charland, Zhongwei Zhang, Kristen M.S. O’Connell, Laura G. Reinholdt, Martín F. Pera

Science Advances

Chromosome X Dosage Modulates Development of Aneuploidy in Genetically Diverse Mouse Embryonic Stem Cells

Preprint

Alexander R. Stanton, Selcan Aydin, Daniel A. Skelly, Dylan Stavish, K Léonhard, Seth M. Taapken, Erik McIntire, Matthew Pankratz, Anne Czechanski, Tenneille E. Ludwig, Ted Choi, Steven P. Gygi, Ivana Barbaric, Steven C. Munger, Laura G. Reinholdt, Martín F. Pera

Genetic dissection of the pluripotent proteome through multi-omics data integration

Article

Cell Genomics · 2023

Selcan Aydin, Duy T. Pham, Tian Zhang, Gregory R. Keele, Daniel A. Skelly, João A. Paulo, Matthew Pankratz, Ted Choi, Steven P. Gygi, Laura G. Reinholdt, Christopher L. Baker, Gary A. Churchill, Steven C. Munger

An in vitro neurogenetics platform for precision disease modeling in the mouse

Preprint

Daniel Cortés, Mélanie Escudero, Austin C. Korgan, Alyssa Edwards, Selcan Aydin, Steven C. Munger, Kevin Charland, Zhongwei Zhang, Kristen M.S. O’Connell, Laura G. Reinholdt, Martín F. Pera

Genetic dissection of the pluripotent proteome through multi-omics data integration

Preprint

Selcan Aydin, Duy T. Pham, Tian Zhang, Gregory R. Keele, Daniel A. Skelly, Matthew Pankratz, Ted Choi, Steven P. Gygi, Laura G. Reinholdt, Christopher L. Baker, Gary A. Churchill, Steven C. Munger

Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency

Article

Cell stem cell · 2020

Daniel A. Skelly, Anne Czechanski, Candice Byers, Selcan Aydin, Catrina Spruce, Chris Olivier, Kwangbom Choi, Daniel M. Gatti, Narayanan Raghupathy, Gregory R. Keele, Alexander R. Stanton, Matthew Vincent, Stephanie Dion, Ian Greenstein, Matthew Pankratz, Devin K. Porter, Whitney Martin, Callan O’connor, Wenning Qin, Alison H. Harrill, Ted Choi, Gary A. Churchill, Steven C. Munger, Christopher L. Baker, Laura G. Reinholdt

Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation

Article

Cell stem cell · 2020

Daniel Ortmann, Stephanie Brown, Anne Czechanski, Selcan Aydin, Daniele Muraro, Yuanhua Huang, Rute A. Tomaz, Anna Osnato, Giovanni Canu, Brandon T. Wesley, Daniel A. Skelly, Oliver Stegle, Ted Choi, Gary A. Churchill, Christopher L. Baker, Peter J. Rugg‐Gunn, Steven C. Munger, Laura G. Reinholdt, Ludovic Vallier

Genetic variation influences pluripotent ground state stability in mouse embryonic stem cells through a hierarchy of molecular phenotypes

Preprint

Daniel A. Skelly, Anne Czechanski, Candice Byers, Selcan Aydin, Catrina Spruce, Chris Olivier, Kwangbom Choi, Daniel M. Gatti, Narayanan Raghupathy, Alexander R. Stanton, Matthew Vincent, Stephanie Dion, Ian Greenstein, Matthew Pankratz, Devin K. Porter, Whitney Martin, Wenning Qin, Alison H. Harrill, Ted Choi, Gary A. Churchill, Steven C. Munger, Christopher L. Baker, Laura G. Reinholdt

Different Mechanisms Confer Gradual Control and Memory at Nutrient- and Stress-Regulated Genes in Yeast

Article

Molecular and Cellular Biology · 2015

Alessandro Rienzo, Daniel Poveda-Huertes, Selcan Aydin, Nicolas E. Buchler, Amparo Pascual‐Ahuir, Markus Proft

Molecular and Cellular Biology